Reading path
Reading the Evidence in Lung and Breathing Disease
This path teaches you to read respiratory evidence from the spirometry report up, covering how airflow is measured, how COPD and asthma are told apart, and how trials settle which treatments actually help. It suits readers who want to understand lung-function numbers and appraise the studies behind inhalers, oxygen, and biologics.
The path, step by step
Begin with the single ratio at the heart of every spirometry report, because it anchors both diagnosis and treatment decisions.
Next see how the chosen cutoff for that ratio can overdiagnose older adults and underdiagnose younger ones.
3 What the DLCO Test Reveals About Gas Transfer
4 min readAdd a second core lung-function test so you can read gas transfer alongside airflow.
4 How the Evidence Separates COPD From Asthma
4 min readWith the tests understood, learn how the evidence distinguishes two conditions that often look alike but are treated differently.
Move into treatment by seeing how a blood biomarker predicts which COPD patients actually benefit from inhaled steroids.
Practice reading a mortality signal by examining whether triple inhaler therapy truly lowered COPD deaths or reflected comparator design.
Broaden beyond drugs to appraise the trial evidence for a non-pharmacologic intervention that changes how patients feel and function.
Continue with another common therapy, testing how trials define who genuinely gains from long-term oxygen.
9 How Biomarkers Pick a Biologic for Severe Asthma
4 min readShift to asthma and see how biomarkers now steer the choice of biologic in severe disease.
Finish with a case study of evidence overturning long-standing practice, tying the whole path back to how guidelines change.
Each step is a full article on the Reading the Evidence blog.